Computational methods in Protein Structural Biophysics

Course

Lecturer:
Lorenzo Di Rienzo (Istituto Italiano di Tecnologia, Center for Life Nano & Neuro Science@Sapienza di Roma)

Board Contact:
Federico Fogolari

SSD: FIS/07

CFU: 3 CFU + assignment: 2 CFU 

Period: July 2025: 07/07/2025: 14.30–17.30 // 08/07/2025: 14.30–17.30 // 09/07/2025: 14.30–17.30 // 10/07/2025: 14.30–17.30

Lessons / Hours: 12 hours, 4 Lectures

Program:

0. How the cell store, transfer and use information: from DNA to proteins (2 h)

1. Evolution and Sequence Similarity (2 h)

2. Protein Structure Prediction (2 h)

3. One Structure or an ensemble of Structures? (2 h)

4. Protein Interactions (2 h)

5. Protein Design (2 h)